This learning activity explores the management of chronic health conditions in school settings, focusing on the crucial role of school nurses. It covers the most prevalent chronic conditions among school-age children, including asthma, diabetes, food allergies, and ADHD. The learning activity details the multifaceted responsibilities of school nurses, encompassing assessment, care coordination, development of Individualized Healthcare Plans, medication management, health education, advocacy, and emergency preparedness. It emphasizes the importance of collaboration with families, healthcare providers, and school staff to ensure comprehensive care for students with chronic conditions. The learning activity concludes by highlighting the significance of school nurses in creating supportive environments that enable students with chronic conditions to thrive academically and socially.