This learning activity provides a comprehensive overview of mental health crisis management for nurses across all practice settings. It establishes that mental health care is integral to holistic nursing practice, not just a specialized skill. The content covers: recognizing early warning signs along a continuum, implementing the SAFER-R assessment and intervention model (Stabilize, Acknowledge, Facilitate, Encourage, Recover/Refer, Restore), applying therapeutic communication strategies during crises, and documenting appropriately using trauma-informed approaches. Through realistic case examples (Maria, Natalie, Dev, Jason, Elena), the essay demonstrates practical application of these concepts in various clinical scenarios. It emphasizes the importance of therapeutic presence, verbal de-escalation, cultural humility, and strength-based documentation. The learning activity concludes by reinforcing that skilled mental health support represents an essential component of nursing care in all environments, not just psychiatric settings.