This learning activity equips school nurses to translate current infectious disease surveillance trends - including measles resurgence, invasive group A strep, and drifted influenza strains - into practical, everyday school health practice. It presents a framework for building durable systems across four core functions: surveillance, prevention, response, and community coordination, with concrete guidance on exclusion criteria, isolation protocols, outbreak preparedness planning, and stigma-free family communication. Rather than focusing on any single pathogen, the content emphasizes adaptable habits and structures that prepare nurses to respond confidently to whatever emerging threat arises next.