This comprehensive learning activity explores tracheostomy and mechanical ventilation care in pediatric patients, covering indications, equipment, principles, and best practices. It equips nurses with essential knowledge for assessment, monitoring, and care delivery, emphasizing patient safety and evidence-based techniques. The content addresses both clinical skills and psychosocial aspects, including family education and complication management, providing a holistic approach to caring for this vulnerable population. Designed for nursing professionals seeking to enhance their expertise, the learning activity offers a thorough foundation for delivering high-quality, compassionate care to children requiring respiratory support.